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Title: Rina Ariga — Radcliffe Department of Medicine
Description: MBBS BSc (Hons) DPhil MRCP Rina Ariga - NIHR Academic Clinical Lecturer in Cardiovascular Medicine
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Texto: Rina Ariga — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Site Map Accessibility Cookies Contact us Log in Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Rina Ariga Contact information Email rina.ariga@cardiov.ox.ac.uk Research groups Neubauer Group: Oxford Centre for Clinical Magnetic Resonance Research Watkins Group: Inherited Heart Muscle Disease Group Colleges The Queen's College Rina Ariga MBBS BSc (Hons) DPhil MRCP NIHR Academic Clinical Lecturer in Cardiovascular Medicine Extraordinary Junior Research Fellow in Pathology, The Queen's College, Oxford Specialist Registrar in Cardiology, John Radcliffe Hospital My research interest is in integrating high-dimensional data from imaging, electrocardiograms (ECG), genetics, blood analysis and health records of patients with cardiovascular disease to gain a better understanding of the underlying pathophysiology. My work is currently focused on the most common inherited heart disease – Hypertrophic Cardiomyopathy (HCM), which is an important cause of sudden cardiac death in young people.  My doctoral research pioneered a novel imaging method for HCM patients to measure heart muscle disarray  – a microstructural abnormality previously only seen at post mortem, which is believed to be the focus for fatal heart rhythms. I have received several prizes and awards for this work, and the findings were reported in the media. I have also demonstrated, in collaboration with Oxford’s Computational Cardiovascular Science Team, a machine learning approach to the ECG to detect subtle electrical changes indicative of such structural defects, and the risk of abnormal rhythms. We used computational modelling and simulation of the heart based on magnetic resonance imaging to reveal distinct mechanisms for specific electrical patterns, which may pave the way towards individualised patient treatment. My ongoing work is in the development of disarray imaging for use in a multicentre prospective study and the application of machine learning in ECG and multiparametric cardiac magnetic resonance imaging. Key publications Identification of Myocardial Disarray in Patients With Hypertrophic Cardiomyopathy and Ventricular Arrhythmias. Journal article Ariga R. et al, (2019), J Am Coll Cardiol, 73, 2493 - 2502 Distinct ECG Phenotypes Identified in Hypertrophic Cardiomyopathy Using Machine Learning Associate With Arrhythmic Risk Markers. Journal article Lyon A. et al, (2018), Front Physiol, 9 Electrocardiogram phenotypes in hypertrophic cardiomyopathy caused by distinct mechanisms: apico-basal repolarization gradients vs. Purkinje-myocardial coupling abnormalities. Journal article Lyon A. et al, (2018), Europace, 20, iii102 - iii112 Recent publications Reply: CMR Assessment of Myocyte Disarray in HCM: Matching Another Piece in the Puzzle. Journal article Ariga R. et al, (2019), J Am Coll Cardiol, 74 Identification of Myocardial Disarray in Patients With Hypertrophic Cardiomyopathy and Ventricular Arrhythmias. Journal article Ariga R. et al, (2019), J Am Coll Cardiol, 73, 2493 - 2502 REAPPRAISING REMODELLING PATTERN OF LEFT VENTRICLE IN AORTIC STENOSIS: AXIS ORIENTATION AS A UNIQUE SIGNATURE OF POSITIVE REMODELLING Conference paper Chan K. et al, (2019), HEART, 105, A18 - A18 STRESS MYOCARDIAL OXYGENATION AND NOT PERFUSION RESERVE DETERMINES ARRHYTHMIC RISK IN HYPERTROPHIC CARDIOMYOPATHY: INSIGHTS FROM A NOVEL OXYGEN-SENSITIVE CMR APPROACH Conference paper Raman B. et al, (2019), HEART, 105, A183 - A183 IMPAIRED STRESS-INDUCED OXYGENATION IN HYPERTROPHIC CARDIOMYOPATHY IS ASSOCIATED WITH AN INCREASED RISK OF VENTRICULAR ARRHYTHMIA Conference paper Raman B. et al, (2019), HEART, 105, A18 - A20 More publications © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement Site Map Accessibility Cookies Contact us Log in About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group Chapman Group: Genome stability and DNA repair mechanisms in cancer and genome diversification People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Affaf Aliouat Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Carole Bataille Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard Jordan Becker John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand Matt Brechin Serena Briant Linford Briant Anne Bridgeman Paul Brodersen James Brown Jill Brown Connor Broyles Marella de Bruijn Alastair Buchan Veronica Buckle Paul Buckley Daniel Bulte Martijn van de Bunt Mario Buono Holger Burchert Emma Burke-Smith Oliver Burns Matthew Burrage Shijie Cai David Cain Sarah Califano Ivan Candido-Ferreira Fang Cao Maria Carena Maria Carena Ricardo Carnicer Davide Carone Joana Carrelha Brigid Carter Barbara Casadei Carla Cascone Vincenzo Cerundolo Kuan Cha Hedia Chagraoui Jem Chalk Keith Channon Ross Chapman Lise Chauveau Jane Cheeseman Yi-Ling Chen Jili Chen Qian Cheng Amy Chiu Robin Choudhury Constantinos Christodoulides Zoe Christodoulou Sandy Chu Surawee Chuaiphichai Aldo Ciau-Uitz Thomas Clague Sally-Ann Clark Kevin Clark Lynn Clee Liz Cloke Christopher Cole Ruth Coleman Huw Colin-York Michela Colombo Ismael da Conceicao Catriona Conway Daniel Cooke Kerrie Cope Anna Corby Thomas Cornfield Eduardo Calpena Corpas Yvonne Couch Mark Crabtree Fay Croft Heidi Crook Eloise Cross Nicholas Crump Andres Hueso Cuervo Nicola Curry Melinda Czéh Liangti Dai Andrea van Dam Rinita Dam Matt Daniels Lorna Daniels Carol Davey James Davies Graham Davies Simon Davis James Dean Rebecca Dean


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