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Title: Naveed Akbar — Radcliffe Department of Medicine
Description: PhD, MSc, BSc (Hons) Naveed Akbar - Postdoctoral Researcher
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Texto: Naveed Akbar — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Site Map Accessibility Cookies Contact us Log in Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Naveed Akbar Contact information Email naveed.akbar@cardiov.ox.ac.uk Research groups Choudhury Group: Understanding Inflammatory processes in Atherosclerosis and Acute Myocardial Infarction Colleges Somerville College Research groups Choudhury Group: Understanding Inflammatory processes in Atherosclerosis and Acute Myocardial Infarction Naveed Akbar PhD, MSc, BSc (Hons) Postdoctoral Researcher Biography I obtained my BSc (Hons) in Human Biology before completing an MSc by research in Biomedical Sciences, where I developed an interest in vascular biology and undertook interdisciplinary training to synthesize and fabricate nanoparticles for vascular targeting. I went on to obtain my PhD in Medicine and Therapeutics at the University of Dundee, where I investigated the role of innate immune signalling cascades in vascular inflammation using in vivo imaging. As a senior postdoctoral scientist in the group of Professor Robin Choudhury, a former Fulford Junior Research Fellow and Tutor in Medicine at Somerville College I investigate the role of extracellular vesicles in inflammation. Cells within our body can transcribe, package and deliver messages to other cells, through the generation of nano-sized bubble-shaped envelopes, called extracellular vesicles (EVs). Within their enclosed spheres, these messages contain potent instructions that can alter the behaviour and biological function of its recipients, which include the very motile and sensitive cells of the immune system. I am uncovering how these shielded messages provoke the immune system into action after a heart attack. Immune system activation after a heart attack directly contributes to further injury and this in turn impacts patient health and well-being. Extracellular vesicles may provide diagnostic potential to better stratify patients for treatment following injury to the heart and as tools for therapeutic targeting. Public Engagement  Pint of Science (pintofscience.co.uk) aims to encourage and support the communication of the latest research in Oxford to the public in an interesting, engaging and approachable way, by bringing scientists to pubs. We attract over 800 attendees to 19 events every year. At Oxford, the festival is led and entirely run by researcher volunteers, rather than being led by a public engagement officer or organisation. I have coordinated our activities in Oxford for the past 6 years. To date Oxford Pint of Science has helped >200 researchers to particpapate in public enagement activities, enabling them to undertake further public enagement events of their own across the UK. Recent publications Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance. Journal article Azzimato V. et al, (2020), Sci Transl Med, 12 British Cardiovascular Society Young Investigator Award 2019. Journal article Page DJ. et al, (2019), Heart, 105, 1841 - 1842 Extracellular vesicles in metabolic disease. Journal article Akbar N. et al, (2019), Diabetologia Gold-coated plant virus as computed tomography imaging contrast agent Journal article Aljabali AAA. et al, (2019), Beilstein Journal of Nanotechnology, 10, 1983 - 1993 T2 mapping MRI technique quantifies carotid plaque lipid, and its depletion after statin initiation, following acute myocardial infarction. Journal article Alkhalil M. et al, (2018), Atherosclerosis, 279, 100 - 106 Exacerbation of Acute Traumatic Brain Injury by Circulating Extracellular Vesicles. Journal article Hazelton I. et al, (2018), J Neurotrauma, 35, 639 - 651 Technical challenges of working with extracellular vesicles. Journal article Ramirez MI. et al, (2018), Nanoscale, 10, 881 - 906 Extracellular vesicles released following heat stress induce bystander effect in unstressed populations Journal article Bewicke-Copley F. et al, (2017), Journal of Extracellular Vesicles, 6 Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction. Journal article Akbar N. et al, (2017), JCI Insight, 2 Circulating endothelial cell-derived extracellular vesicles mediate the acute phase response and sickness behaviour associated with CNS inflammation. Journal article Couch Y. et al, (2017), Sci Rep, 7 Inflammatory Stroke Extracellular Vesicles Induce Macrophage Activation. Journal article Couch Y. et al, (2017), Stroke, 48, 2292 - 2296 ENDOTHELIUM-DERIVED EXTRACELLULAR VESICLES PROMOTE SPLENIC MONOCYTE MOBILISATION IN MYOCARDIAL INFARCTION Conference paper Akbar N. et al, (2017), HEART, 103, A150 - A150 An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice. Journal article Akbar N. et al, (2015), Arthritis Res Ther, 17 In vivo noninvasive measurement of skin autofluorescence biomarkers relate to cardiovascular disease in mice. Journal article Akbar N. et al, (2014), J Microsc, 255, 42 - 48 Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo. Journal article Belch JJF. et al, (2013), Microvasc Res, 85, 86 - 92 Biocompatibility of amorphous silica nanoparticles: Size and charge effect on vascular function, in vitro. Journal article Akbar N. et al, (2011), Biotechnol Appl Biochem, 58, 353 - 362 More publications © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement Site Map Accessibility Cookies Contact us Log in About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group Chapman Group: Genome stability and DNA repair mechanisms in cancer and genome diversification Patel Group People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Affaf Aliouat Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard Jordan Becker John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand


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