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Title: Merve Aksoz — Radcliffe Department of Medicine
Description: MSc (Hons) BSc (Hons) Merve Aksoz - DPhil Student
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Texto: Merve Aksoz — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Skip to main content Site Map Accessibility Cookies Contact us Log in Menu Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Merve Aksoz Contact information Email merve.aksoz@rdm.ox.ac.uk Telephone +44 (0)1865 222575 Research groups Nerlov Group: Hematopoietic Stem Cell Genetics Colleges Linacre College Websites WIMM Graduate Student Association WIMM Women in Science Committee Merve Aksoz MSc (Hons) BSc (Hons) DPhil Student WIMM Graduate Student Association- Social Secretary WIMM Women in Science Committee- Representative of WIMM Students Linacre college - Green Student ( Behavioral Change) & President of Green Society I am a DPhil student in Nerlov lab since April 2017.  My work will explore human HSC (hHSC) heterogeneity with the aim of identifying gene signatures and surface markers that could allow hHSC subsets to be identified.  The human hematopoietic stem cell is the basis for the most common stem cell-based therapy in clinical practice, namely bone marrow transplantation. However, hHSC remains poorly described, limiting our ability to evaluate the quality of donor cell preparations, including the number of reconstituting hHSCS they contain and their capacity to rapidly reconstitute the cell types (neutrophils, platelets) critical for patient recovery.  Improved understanding of human hematopoietic stem cell biology will contribute to the treatment of both congenital and acquired blood disorders. In particular, better definition of hHSCs will facilitate efforts to genome edit hHSCs in congenital blood disorders, and improve donor selection for bone marrow transplantation Recent publications c-Myc inhibitor 10074-G5 induces murine and human hematopoietic stem and progenitor cell expansion and HDR modulator Rad51 expression. Journal article Aksoz M. et al, (2018), Curr Cancer Drug Targets Identification of cardiogenic factors modulated during neonatal cardiac regeneration Conference paper Kocabas F. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S16 - S16 Emerging Roles of Meis1 in Cardiac Regeneration, Stem Cells and Cancer. Journal article Aksoz M. et al, (2018), Curr Drug Targets, 19, 181 - 190 More publications © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Carole Bataille Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Nicolas Bery Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand Matt Brechin Serena Briant Linford Briant Anne Bridgeman Paul Brodersen James Brown Jill Brown Connor Broyles Marella de Bruijn Alastair Buchan Veronica Buckle Paul Buckley Daniel Bulte Martijn van de Bunt Mario Buono Holger Burchert Emma Burke-Smith Oliver Burns Matthew Burrage Shijie Cai David Cain Sarah Califano Ivan Candido-Ferreira Fang Cao Maria Carena Maria Carena Ricardo Carnicer Davide Carone Joana Carrelha Brigid Carter Barbara Casadei Carla Cascone Vincenzo Cerundolo Kuan Cha Hedia Chagraoui Jem Chalk Keith Channon Lise Chauveau Jane Cheeseman Yi-Ling Chen Jili Chen Qian Cheng Amy Chiu Robin Choudhury Constantinos Christodoulides Zoe Christodoulou Sandy Chu Surawee Chuaiphichai Aldo Ciau-Uitz Thomas Clague Sally-Ann Clark Kevin Clark Lynn Clee Liz Cloke Christopher Cole Ruth Coleman Huw Colin-York Michela Colombo Ismael da Conceicao Catriona Conway Daniel Cooke Kerrie Cope Anna Corby Thomas Cornfield Eduardo Calpena Corpas Yvonne Couch Mark Crabtree Fay Croft Heidi Crook Eloise Cross Nicholas Crump Andres Hueso Cuervo Melinda Czéh Liangti Dai Andrea van Dam Rinita Dam Matt Daniels Lorna Daniels Carol Davey James Davies Graham Davies Simon Davis James Dean Rebecca Dean Atanasiu Stefan Demian Niall Dempster Louise Dennis Timothy Dent Geoffrey Denwood Michael Desborough Veronica Alcolea Devesa Matthew Dickinson Marina Diotallevi Tomasz Dobrzycki Cameron Dockerill Michael Dodd Kathleen Dolan Hamid Dolatshad Robert Friedrich Donat Tao Dong Patricia Douglas Gillian Douglas Damien Downes Hal Drakesmith Roy Drissen Edward Drydale Yue Du Claire Duff Sam Dunkley Pamela Dyson James Early James Eaton Carol Eaton Laurienne Edgar Christian Eggeling Mehroz Ehsan Jane Ellis Hanif Esmail Lise Estcourt Rachel Etherington Mark Evans Tracey Evans Martyn Ezra Anne Farmer Martin Farrall Martin Fellermeyer Candida Fenton David Ferguson João Ferreira Fernandes Vanessa Ferreira Lucy Field Alison Fletcher Gary Ford Nicholas Fordham Helena Francis John Frankland Rachel Franklin Joe Frost Xiaopeng Fu Lars Fugger Lars Fugger Tudor Fulga Kezia Gaitskell Parag Gajendragadkar Silvia Galiani Toby Gamlen Jonathan Gamwell Wei Gan


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269 www.rdm.ox.ac.uk/people/claire-duff
270 www.rdm.ox.ac.uk/people/samuel-dunkley
271 www.rdm.ox.ac.uk/people/pamela-dyson
272 www.rdm.ox.ac.uk/people/james-early
273 www.rdm.ox.ac.uk/people/james-eaton
274 www.rdm.ox.ac.uk/people/carol-eaton
275 www.rdm.ox.ac.uk/people/laurienne-gardner
276 www.rdm.ox.ac.uk/people/christian-eggeling
277 www.rdm.ox.ac.uk/people/mehroz-ehsan
278 www.rdm.ox.ac.uk/people/jane-ellis
279 www.rdm.ox.ac.uk/people/hanif-esmail
280 www.rdm.ox.ac.uk/people/lise-estcourt
281 www.rdm.ox.ac.uk/people/rachel-etherington
282 www.rdm.ox.ac.uk/people/mark-evans
283 www.rdm.ox.ac.uk/people/tracey-evans
284 www.rdm.ox.ac.uk/people/martyn-ezra
285 www.rdm.ox.ac.uk/people/anne-farmer
286 www.rdm.ox.ac.uk/people/martin-farrall
287 www.rdm.ox.ac.uk/people/martin-fellermeyer
288 www.rdm.ox.ac.uk/people/candida-fenton
289 www.rdm.ox.ac.uk/people/david-ferguson
290 www.rdm.ox.ac.uk/people/joao-ferreira-fernandes
291 www.rdm.ox.ac.uk/people/vanessa-ferreira
292 www.rdm.ox.ac.uk/people/lucy-field
293 www.rdm.ox.ac.uk/people/alison-fletcher
294 www.rdm.ox.ac.uk/people/gary-ford
295 www.rdm.ox.ac.uk/people/nicholas-fordham
296 www.rdm.ox.ac.uk/people/helena-francis
297 www.rdm.ox.ac.uk/people/john-frankland
298 www.rdm.ox.ac.uk/people/rachel-franklin
299 www.rdm.ox.ac.uk/people/joe-frost
300 www.rdm.ox.ac.uk/people/xiaopeng-fu
301 www.rdm.ox.ac.uk/people/lars-fugger
302 www.rdm.ox.ac.uk/people/lars-fugger-1
303 www.rdm.ox.ac.uk/people/tudor-fulga
304 www.rdm.ox.ac.uk/people/kezia-gaitskell
305 www.rdm.ox.ac.uk/people/parag-gajendragadkar-1
306 www.rdm.ox.ac.uk/people/silvia-galiani
307 www.rdm.ox.ac.uk/people/toby-gamlen-1
308 www.rdm.ox.ac.uk/people/jonathan-gamwell
309 www.rdm.ox.ac.uk/people/wei-gan



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