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Title: Martijn van de Bunt — Radcliffe Department of Medicine
Description: Martijn van de Bunt - Novo Nordisk Postdoctoral Research Fellow (2014-2017)
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Texto: Martijn van de Bunt — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Site Map Accessibility Cookies Contact us Log in Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Martijn van de Bunt Contact information Email mjvb@novonordisk.com Martijn van de Bunt Novo Nordisk Postdoctoral Research Fellow (2014-2017) Project: Insights into type 2 diabetes pathogenesis through transcriptomic and functional analysis of the developing human islet Biography Martijn was awarded a Novo Nordisk Postdoctoral Research Fellowship, working with Professors Mark McCarthy and Anna Gloyn at the Oxford Centre for Diabetes, Endocrinology & Metabolism and the Wellcome Trust Centre for Human Genetics. His research aimed to improve understanding of islet biology and pathophysiology through the integrative analysis of large genomic datasets on key type 2 diabetes tissues with findings from human genetics. Martijn’s work led to significant advances in understanding of type 2 diabetes and glycaemic trait genome-wide association loci – for example identifying a novel regulator of insulin secretion, ZMIZ1. Martijn was awarded a prestigious American Society for Human Genetics (ASHG) Charles J Epstein Trainee Award for Excellence in Human Genetics Research. Following his Novo Nordisk fellowship at the University of Oxford, Martijn moved to Novo Nordisk, Copenhagen, in May 2017. He joined the Global Research Unit as an Informatics Specialist to provide bioinformatics expertise for target discovery and validation efforts and to develop broader new initiatives within that realm. PUBLICATIONS Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation Gamazon ER, Segrè AV, van de Bunt M et al, (2018) Nature Genetics Patterns of differential gene expression in a cellular model of human islet development, and relationship to type 2 diabetes predisposition Perez-Alcantara M,… van de Bunt M, (2018) Diabetologia Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study Gudmundsdottir V,… van de Bunt M et al, (2018) PLOS One Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci Thurner M, van de Bunt M et al, (2018) eLIFE Sequence data and association statistics from 12,940 type 2 diabetes cases and controls Flannick J,… van de Bunt et al, (2018) Scientific Data Characterising cis -regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues Zhang MF,… van de Bunt M et al, (2017) Gut A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk Manning A,… van de Bunt M et al, (2017) Diabetes Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice. American Journal of Human Genetics Carrat GR,… van de Bunt M et al, (2017) The American Journal of Human Genetics Colocalization of GWAS and eQTL Signals Detects Target Genes Hormozdiari F, van de Bunt M et al, (2016) AJHG Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance Lotta LA,… van de Bunt M et al, (2016) Nature Genetics An alternative effector gene at the type 2 diabetes-associated TCF7L2 locus? van de Bunt M (2016) Diabetologia Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants Thomsen SK, Ceroni A, van de Bunt M et al, (2016) Diabetes The genetic architecture of type 2 diabetes Fuchsberger C,… van de Bunt M et al, (2016) Nature Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model van de Bunt M et al, (2016) Islets Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation Szabat M,… van de Bunt M et al, (2016) Cell Metabolism Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors van de Bunt M et al, (2015) PLOS Genetics   © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement Site Map Accessibility Cookies Contact us Log in About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working 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246 www.rdm.ox.ac.uk/people/eloise-cross
247 www.rdm.ox.ac.uk/people/nicholas-crump
248 www.rdm.ox.ac.uk/people/andres-hueso-cuervo
249 www.rdm.ox.ac.uk/people/nicola-curry
250 www.rdm.ox.ac.uk/people/melinda-czeh
251 www.rdm.ox.ac.uk/people/liangti-dai
252 www.rdm.ox.ac.uk/people/andrea-vandam
253 www.rdm.ox.ac.uk/people/rinita-dam
254 www.rdm.ox.ac.uk/people/matthew-daniels
255 www.rdm.ox.ac.uk/people/lorna-daniels
256 www.rdm.ox.ac.uk/people/carol-davey
257 www.rdm.ox.ac.uk/people/james-davies
258 www.rdm.ox.ac.uk/people/graham-davies
259 www.rdm.ox.ac.uk/people/simon-davis
260 www.rdm.ox.ac.uk/people/james-dean
261 www.rdm.ox.ac.uk/people/rebecca-dean
262 www.rdm.ox.ac.uk/people/atanasiu-stefan-demian
263 www.rdm.ox.ac.uk/people/niall-dempster
264 www.rdm.ox.ac.uk/people/louise-dennis
265 www.rdm.ox.ac.uk/people/timothy-dent
266 www.rdm.ox.ac.uk/people/geoffrey-denwood
267 www.rdm.ox.ac.uk/people/michael-desborough
268 www.rdm.ox.ac.uk/people/matthew-dickinson
269 www.rdm.ox.ac.uk/people/marina-diotallevi
270 www.rdm.ox.ac.uk/people/tomasz-dobrzycki
271 www.rdm.ox.ac.uk/people/cameron-dockerill
272 www.rdm.ox.ac.uk/people/michael-dodd
273 www.rdm.ox.ac.uk/people/kathleen-dolan
274 www.rdm.ox.ac.uk/people/hamid-dolatshad
275 www.rdm.ox.ac.uk/people/robert-friedrich-donat
276 www.rdm.ox.ac.uk/people/tao-dong
277 www.rdm.ox.ac.uk/people/greig-dougall
278 www.rdm.ox.ac.uk/people/patricia-douglas
279 www.rdm.ox.ac.uk/people/gillian-douglas
280 www.rdm.ox.ac.uk/people/damien-downes
281 www.rdm.ox.ac.uk/people/alexander-drakesmith
282 www.rdm.ox.ac.uk/people/roy-drissen
283 www.rdm.ox.ac.uk/people/edward-drydale
284 www.rdm.ox.ac.uk/people/yue-du
285 www.rdm.ox.ac.uk/people/claire-duff
286 www.rdm.ox.ac.uk/people/samuel-dunkley
287 www.rdm.ox.ac.uk/people/pamela-dyson
288 www.rdm.ox.ac.uk/people/james-early
289 www.rdm.ox.ac.uk/people/james-eaton
290 www.rdm.ox.ac.uk/people/carol-eaton
291 www.rdm.ox.ac.uk/people/laurienne-gardner
292 www.rdm.ox.ac.uk/people/christian-eggeling
293 www.rdm.ox.ac.uk/people/mehroz-ehsan
294 www.rdm.ox.ac.uk/people/jane-ellis
295 www.rdm.ox.ac.uk/people/hanif-esmail
296 www.rdm.ox.ac.uk/people/lise-estcourt
297 www.rdm.ox.ac.uk/people/rachel-etherington
298 www.rdm.ox.ac.uk/people/mark-evans
299 www.rdm.ox.ac.uk/people/tracey-evans
300 www.rdm.ox.ac.uk/people/martyn-ezra
301 www.rdm.ox.ac.uk/people/anne-farmer
302 www.rdm.ox.ac.uk/people/martin-farrall
303 www.rdm.ox.ac.uk/people/oliver-featherstone
304 www.rdm.ox.ac.uk/people/martin-fellermeyer
305 www.rdm.ox.ac.uk/people/candida-fenton
306 www.rdm.ox.ac.uk/people/david-ferguson
307 www.rdm.ox.ac.uk/people/joao-ferreira-fernandes



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