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Title: Marella de Bruijn — Radcliffe Department of Medicine
Description: Marella de Bruijn - Professor of Developmental Haematopoiesis
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Texto: Marella de Bruijn — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Skip to main content Site Map Accessibility Cookies Contact us Log in Menu Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Marella de Bruijn Contact information Email marella.debruijn@imm.ox.ac.uk Telephone +44 (0)1865 222397 Research groups de Bruijn Group: Developmental Haematopoiesis Colleges Green Templeton College Websites MRC Molecular Haematology Unit Research Unit MRC Weatherall Institute of Molecular Medicine Research Institute DPHIL SUPERVISOR PROFILE de Bruijn Group - Developmental Haematopoiesis Marella de Bruijn Professor of Developmental Haematopoiesis Director of Graduate Studies I obtained my BSc in Biomedical Sciences from Leiden University and my PhD from Erasmus University, Rotterdam, the Netherlands, where I trained in Immunology. I was a Post-Doctoral Fellow at the Department of Cell Biology and Genetics at Erasmus University, and a Fellow of the Dutch Cancer Society at Dartmouth Medical School, Hanover, NH. In 2003 I moved to Oxford to join the faculty of the MRC Molecular Haematology Unit at the MRC Weatherall Institute of Molecular Medicine.  My main research interest is the birth of blood stem and progenitor cells during embryonic development. Work in my group focuses on the cellular lineages and gene regulatory networks that underlie the de novo generation of blood stem cells, with the ultimate aim to contribute this knowledge to the development of novel and improved stem cell therapies for regenerative medicine. As Principal Investigator at the MRC Molecular Haematology Unit, I have trained DPhil students and postdocs, and undergraduates that visit the lab for short projects. Along my research I have been actively involved in coordinating the recruitment, training and supervision of DPhil students, as Director of Graduate Studies at the Radcliffe Department of Medicine and WIMM.  Recent publications Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium. Journal article Bonkhofer F. et al, (2019), Nat Commun, 10 Microhomologies are prevalent at Cas9-induced larger deletions Journal article Owens DDG. et al, (2019), Nucleic Acids Research Gata3 targets Runx1 in the embryonic haematopoietic stem cell niche Conference paper Fitch SR. et al, (2019), IUBMB Life Kit ligand has a critical role in mouse yolk sac and aorta-gonad-mesonephros hematopoiesis. Journal article Azzoni E. et al, (2018), EMBO Rep, 19 Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells. Journal article Neo WH. et al, (2018), Blood, 131, 2223 - 2234 More publications © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Carole Bataille Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Nicolas Bery Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand Matt Brechin Serena Briant Linford Briant Anne Bridgeman Paul Brodersen James Brown Jill Brown Connor Broyles Marella de Bruijn Alastair Buchan Veronica Buckle Paul Buckley Daniel Bulte Martijn van de Bunt Mario Buono Holger Burchert Emma Burke-Smith Oliver Burns Matthew Burrage Shijie Cai David Cain Sarah Califano Ivan Candido-Ferreira Fang Cao Maria Carena Maria Carena Ricardo Carnicer Davide Carone Joana Carrelha Brigid Carter Barbara Casadei Carla Cascone Vincenzo Cerundolo Kuan Cha Hedia Chagraoui Jem Chalk Keith Channon Lise Chauveau Jane Cheeseman Yi-Ling Chen Jili Chen Qian Cheng Amy Chiu Robin Choudhury Constantinos Christodoulides Zoe Christodoulou Sandy Chu Surawee Chuaiphichai Aldo Ciau-Uitz Thomas Clague Sally-Ann Clark Kevin Clark Lynn Clee Liz Cloke Christopher Cole Ruth Coleman Huw Colin-York Michela Colombo Ismael da Conceicao Catriona Conway Daniel Cooke Kerrie Cope Anna Corby Thomas Cornfield Eduardo Calpena Corpas Yvonne Couch Mark Crabtree Fay Croft Heidi Crook Eloise Cross Nicholas Crump Andres Hueso Cuervo Melinda Czéh Liangti Dai Andrea van Dam Rinita Dam Matt Daniels Lorna Daniels Carol Davey James Davies Graham Davies Simon Davis James Dean Rebecca Dean Atanasiu Stefan Demian Niall Dempster Louise Dennis Timothy Dent Geoffrey Denwood Michael Desborough Veronica Alcolea Devesa Matthew Dickinson Marina Diotallevi Tomasz Dobrzycki Cameron Dockerill Michael Dodd Kathleen Dolan Hamid Dolatshad Robert Friedrich Donat Tao Dong Patricia Douglas Gillian Douglas Damien Downes Hal Drakesmith Roy Drissen Edward Drydale Yue Du Claire Duff Sam Dunkley Pamela Dyson James Early James Eaton Carol Eaton Laurienne Edgar Christian Eggeling Mehroz Ehsan Jane Ellis Hanif Esmail Lise Estcourt Rachel Etherington Mark Evans Tracey Evans Martyn Ezra Anne Farmer Martin Farrall Martin Fellermeyer Candida Fenton David Ferguson João Fer


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268 www.rdm.ox.ac.uk/people/alexander-drakesmith
269 www.rdm.ox.ac.uk/people/roy-drissen
270 www.rdm.ox.ac.uk/people/edward-drydale
271 www.rdm.ox.ac.uk/people/yue-du
272 www.rdm.ox.ac.uk/people/claire-duff
273 www.rdm.ox.ac.uk/people/samuel-dunkley
274 www.rdm.ox.ac.uk/people/pamela-dyson
275 www.rdm.ox.ac.uk/people/james-early
276 www.rdm.ox.ac.uk/people/james-eaton
277 www.rdm.ox.ac.uk/people/carol-eaton
278 www.rdm.ox.ac.uk/people/laurienne-gardner
279 www.rdm.ox.ac.uk/people/christian-eggeling
280 www.rdm.ox.ac.uk/people/mehroz-ehsan
281 www.rdm.ox.ac.uk/people/jane-ellis
282 www.rdm.ox.ac.uk/people/hanif-esmail
283 www.rdm.ox.ac.uk/people/lise-estcourt
284 www.rdm.ox.ac.uk/people/rachel-etherington
285 www.rdm.ox.ac.uk/people/mark-evans
286 www.rdm.ox.ac.uk/people/tracey-evans
287 www.rdm.ox.ac.uk/people/martyn-ezra
288 www.rdm.ox.ac.uk/people/anne-farmer
289 www.rdm.ox.ac.uk/people/martin-farrall
290 www.rdm.ox.ac.uk/people/martin-fellermeyer
291 www.rdm.ox.ac.uk/people/candida-fenton
292 www.rdm.ox.ac.uk/people/david-ferguson
293 www.rdm.ox.ac.uk/people/joao-ferreira-fernandes



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