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Title: Chris Groves — Radcliffe Department of Medicine
Description: BSc (Hons) Chris Groves - Laboratory Manager
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Texto: Chris Groves — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Site Map Accessibility Cookies Contact us Log in Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Chris Groves portrait Contact information Email chris.groves@ndm.ox.ac.uk Telephone +44 (0)1865 222907 Chris Groves BSc (Hons) Laboratory Manager Department Safety Officer Biological Safety Officer PD - RDM Investigative Medicine I graduated from the University of Wales College Swansea in 1993 with a BSC in Genetics, and started work in the Diabetes Research Laboratories (DRL) at the Radcliffe Infirmary in March 1994 where I performed immunoassays in support of the many clinical trials being run in the department at that time. I moved to the Wellcome Trust Centre for Human Genetics (WTCHG) in 1996, which at the time was based at the Nuffield Orthopaedic Centre (NOC) campus. I spent 2 years working on a type I diabetes microsatellite genome scan led by Professor Mark Lathrop. In 1998 I returned to the DRL to work in the genetics lab on a complications of type 2 diabetes project led by Professor Robert Turner and introduced techniques for both microsatellite and SNP genotyping. In early 2000 I joined Professor Mark McCarthy’s type 2 diabetes genetics group, then based at the WTCHG (re-located to Old Road Campus), as a research assistant. I went on to perform the role of Laboratory Manager at the Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM), administering the laboratory space occupied by Professors McCarthy and Gloyn’s groups. I facilitated the research performed by the group members, whilst contributing to the groups’ research interests in several national and international consortia (CHARGE, DIAGRAM, EGG, GIANT, GoT2D, MAGIC, WTCCC). I also project managed aspects of an EU funded project (DIRECT) for which Prof McCarthy was work package lead. In 2017 I became Laboratory Manager for the Departments of Experimental Medicine and Investigative Medicine based at the John Radcliffe Hospital where I oversee the day to day operations of our core laboratory which provides support to the departments’ research community. Key publications Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells. Journal article Thomsen SK. et al, (2018), Nat Genet, 50, 1122 - 1131 The genetic architecture of type 2 diabetes. Journal article Fuchsberger C. et al, (2016), Nature, 536, 41 - 47 A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Journal article Frayling TM. et al, (2007), Science, 316, 889 - 894 Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Journal article Zeggini E. et al, (2007), Science, 316, 1336 - 1341 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Journal article Wellcome Trust Case Control Consortium None., (2007), Nature, 447, 661 - 678 Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Journal article Groves CJ. et al, (2006), Diabetes, 55, 2640 - 2644 Recent publications Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium. Journal article Koivula RW. et al, (2019), Diabetologia, 62, 1601 - 1615 Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data. Journal article Romagnoni A. et al, (2019), Sci Rep, 9 Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes. Journal article Juszczak A. et al, (2019), Diabetes Care, 42, 17 - 26 Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells. Journal article Thomsen SK. et al, (2018), Nat Genet, 50, 1122 - 1131 A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. Journal article van Zuydam NR. et al, (2018), Diabetes, 67, 1414 - 1427 More publications © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement Site Map Accessibility Cookies Contact us Log in About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Affaf Aliouat Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Carole Bataille Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand Matt Brechin Serena Briant Linford Briant Anne Bridgeman Paul Brodersen James Brown Jill Brown Connor Broyles Marella de Bruijn Alastair Buchan Veronica Buckle Paul Buckley Daniel Bulte Martijn van de Bunt Mario Buono Holger Burchert Emma Burke-Smith Oliver Burns Matthew Burrage Shijie Cai David Cain Sarah Califano Ivan Candido-Ferreira Fang Cao Maria Carena Maria Carena Ricardo Carnicer Davide Carone Joana Carrelha Brigid Carter Barbara Casadei Carla Cascone Vincenzo Cerundolo Kuan Cha Hedia Chagraoui Jem Chalk Keith Channon Lise Chauveau Jane Cheeseman Yi-Ling Chen Jili Chen Qian Cheng Amy Chiu Robin Choudhury Constantinos Christodoulides Zoe Christodoulou Sandy Chu Surawee Chuaiphichai Aldo Ciau-Uitz Thomas Clague Sally-Ann Clark Kevin Clark Lynn Clee Liz Cloke Christopher Cole Ruth Coleman Huw Colin-York Michela Colombo Ismael da Conceicao Catriona Conway Daniel Cooke Kerrie Cope Anna Corby Thomas Cornfield Eduardo Calpena Corpas Yvonne Couch Mark Crabtree Fay Croft Heidi Crook Eloise Cross Nicholas Crump Andres Hueso Cuervo Nicola Curry Melinda Czéh Liangti Dai Andrea van Dam Rinita Dam Matt Daniels Lorna Daniels


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