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Title: Alison Banham — Radcliffe Department of Medicine
Description: BA, MA, DPhil (Oxon), FRCPath Alison Banham - Professor of Haemato-oncology
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Texto: Alison Banham — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Site Map Accessibility Cookies Contact us Log in Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Alison Banham Contact information Email alison.banham@ndcls.ox.ac.uk Telephone +44 (0)1865 220246 PA Joanne Lavender joanne.lavender@ndcls.ox.ac.uk Research groups Banham Group: Haemato-Oncology Group Alison Banham BA, MA, DPhil (Oxon), FRCPath Professor of Haemato-oncology Head of NDCLS The study of transcriptional de-regulation in B-cell malignancies and the development of novel antibodies for cancer therapy. Alison Banham is currently Professor of Haemato-oncology and Head of the Nuffield Division of Clinical Laboratory Sciences, within the Radcliffe Department of Medicine at the University of Oxford. Her academic qualifications include BA, MA and D.Phil. (PhD) degrees from the University of Oxford and Fellowship of the Royal College of Pathologists.   Professor Banham is a founder member and Vice President of the European Network of Monoclonal Antibody Producing Laboratories. She is internationally recognised for her expertise in the production and characterisation of monoclonal antibodies and has written guidelines to promote effective antibody validation. She has also made key contributions to the design and delivery of EuroMabNet workshops that teach young scientists how to validate antibodies.   Since 1995 Professor Banham's main research focus has been within the field of cancer, particularly aggressive B-cell malignancies, focussing initially on the identification and characterisation of novel diagnostic and prognostic biomarkers. These have included the FOXP family of forkhead transcription factors (FOXP1-4) and the cancer testis antigen PASD1. These de-regulated transcription factors have functional roles in tumour biology and strategies are being investigated to enable their future therapeutic targeting in diffuse large B-cell lymphoma and multiple myeloma.   Professor Banham's team are also generating novel therapeutic antibodies. These include antibodies targeting the tumour vasculature, in particular the Notch ligand Jagged-1 and the adhesion G-protein coupled receptor ELTD1. She is also pursuing the development of TCR mimic antibodies which recognise peptides from intracellular tumour proteins that are presented on the cell surface by MHC class I molecules. This enables targeting of the intracellular proteome and antibodies to the p53 oncosuppressor are being further characterised. Key publications FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas. Journal article Brown PJ. et al, (2016), Leukemia, 30, 605 - 616 The European antibody network's practical guide to finding and validating suitable antibodies for research. Journal article Roncador G. et al, (2016), MAbs, 8, 27 - 36 A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. Journal article Masiero M. et al, (2013), Cancer Cell, 24, 229 - 241 Recent publications CRISPR/Cas9-Mediated Foxp1 Silencing Restores Immune Surveillance in an Immunocompetent A20 Lymphoma Model Journal article FELCE SL. et al, (2020), Frontiers in Oncology, 10 Carbonic anhydrase 9 (CA9) expression in non-small-cell lung cancer: correlation with regulatory FOXP3+T-cell tumour stroma infiltration. Journal article Giatromanolaki A. et al, (2020), Br J Cancer ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile. Journal article Favara DM. et al, (2019), Metabolites, 9 Development of therapeutic anti-JAGGED1 antibodies for cancer therapy. Journal article Masiero M. et al, (2019), Mol Cancer Ther ADGRL4/ELTD1 is a highly conserved angiogenesis-associated orphan adhesion GPCR that emerged with the first vertebrates and comprises 3 evolutionary variants. Journal article Favara DM. et al, (2019), BMC Evol Biol, 19 More publications ORCID 0000-0002-3197-273X © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement Site Map Accessibility Cookies Contact us Log in About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group Chapman Group: Genome stability and DNA repair mechanisms in cancer and genome diversification People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Affaf Aliouat Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Carole Bataille Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard Jordan Becker John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand Matt Brechin Serena Briant Linford Briant Anne Bridgeman Paul Brodersen James Brown Jill Brown Connor Broyles Marella de Bruijn Alastair Buchan Veronica Buckle Paul Buckley Daniel Bulte Martijn van de Bunt Mario Buono Holger Burchert Emma Burke-Smith Oliver Burns Matthew Burrage Shijie Cai David Cain Sarah Califano Ivan Candido-Ferreira Fang Cao Maria Carena Maria Carena Ricardo Carnicer Davide Carone Joana Carrelha Brigid Carter Barbara Casadei Carla Cascone Vincenzo Cerundolo Kuan Cha Hedia Chagraoui Jem Chalk Keith Channon Ross Chapman Lise Chauveau Jane Cheeseman Yi-Ling Chen Jili Chen Qian Cheng Amy Chiu Robin Choudhury Constantinos Christodoulides Zoe Christodoulou Sandy Chu Surawee Chuaiphichai Aldo Ciau-Uitz Thomas Clague Sally-Ann Clark Kevin Clark Lynn Clee Liz Cloke Christopher Cole Ruth Coleman Huw Colin-York Michela Colombo Ismael da Conceicao Catriona Conway Daniel Cooke Kerrie Cope Anna Corby Thomas Cornfield Eduardo Calpena Corpas Yvonne Couch Mark Crabtree Fay Croft Heidi Crook Eloise Cross Nicholas Crump Andres Hueso Cuervo Nicola Curry Melinda Czéh Liangti Dai Andrea van Dam Rinita Dam Matt Daniels Lorna Daniels Carol Davey James Davies Graham Davies Simon Davis James Dean Rebecca Dean Atanasiu Stefan Demian Niall Dempster Louise Dennis Timothy Dent Geoffrey Denwood Michael Desborough Matthew Dickinson Marina Diotallevi Tomasz Dobrzycki Cameron Dockerill Michael Dodd Kathleen Dolan Hamid Dolatshad Robert Friedrich Donat Tao Dong Patricia Douglas Gillian Douglas


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255 www.rdm.ox.ac.uk/people/james-dean
256 www.rdm.ox.ac.uk/people/rebecca-dean
257 www.rdm.ox.ac.uk/people/atanasiu-stefan-demian
258 www.rdm.ox.ac.uk/people/niall-dempster
259 www.rdm.ox.ac.uk/people/louise-dennis
260 www.rdm.ox.ac.uk/people/timothy-dent
261 www.rdm.ox.ac.uk/people/geoffrey-denwood
262 www.rdm.ox.ac.uk/people/michael-desborough
263 www.rdm.ox.ac.uk/people/matthew-dickinson
264 www.rdm.ox.ac.uk/people/marina-diotallevi
265 www.rdm.ox.ac.uk/people/tomasz-dobrzycki
266 www.rdm.ox.ac.uk/people/cameron-dockerill
267 www.rdm.ox.ac.uk/people/michael-dodd
268 www.rdm.ox.ac.uk/people/kathleen-dolan
269 www.rdm.ox.ac.uk/people/hamid-dolatshad
270 www.rdm.ox.ac.uk/people/robert-friedrich-donat
271 www.rdm.ox.ac.uk/people/tao-dong
272 www.rdm.ox.ac.uk/people/patricia-douglas
273 www.rdm.ox.ac.uk/people/gillian-douglas



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