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Title: Alex Antonopoulos — Radcliffe Department of Medicine
Description: Alex Antonopoulos - Visiting Postdoctoral Clinical Researcher
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Texto: Alex Antonopoulos — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Site Map Accessibility Cookies Contact us Log in Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Alex Antonopoulos Contact information Email alexios.antonopoulos@cardiov.ox.ac.uk Research groups Antoniades Group: The Oxford Translational Cardiovascular Research Group Alex Antonopoulos Visiting Postdoctoral Clinical Researcher I am a Postdoctoral Clinical Researcher with a keen interest in the interplay between adipose tissue and the cardiovascular system. My research career in the field of cardiovascular medicine began as a PhD student in the University of Athens, Greece, where I studied the role of adipose tissue-secreted adiponectin in the endothelial function of human vessels. Then in 2011 I received a grant from the European Society of Cardiology and subsequently a Marie Curie Fellowship that allowed me to join Prof. Charalambos Antoniades group in the Division of Cardiovascular Medicine, Radcliffe Department of Medicine as a Postdoctoral Fellow. During those years I expanded my work on adipose tissue by identifying important pathways involved in the cross-talk between epicardial adipose tissue and the heart as well as perivascular adipose tissue and human vessels in patients with ischemic heart disease. These findings further stimulated my interest in the discovery of methods for the non-invasive phenotyping of human adipose tissue in an effort to couple biology with imaging and have resulted in the construction of a computed tomography (CT)-based methodology which allows detection of coronary inflammation by imaging of perivascular fat. Alterations in perivascular fat as a result of vascular inflammation can be tracked by CT imaging and identify vessels at risk for atherosclerosis progression or plaque rupture. This new imaging biomarker may have important clinical implications for the risk stratification and management of patients with both obstructive and non-obstructive coronary artery disease, and its prognostic value is currently being actively explored in large clinical studies.   Recent publications Plasma signature of apoptotic microvesicles is associated with endothelial dysfunction and plaque rupture in acute coronary syndromes. Journal article Zacharia E. et al, (2019), J Mol Cell Cardiol Development of a risk score for early saphenous vein graft failure: An individual patient data meta-analysis. Journal article Antonopoulos AS. et al, (2019), J Thorac Cardiovasc Surg Functional cardiac orexin receptors: role of orexin-B/orexin 2 receptor in myocardial protection. Journal article Patel VH. et al, (2018), Clin Sci (Lond), 132, 2547 - 2564 Cardiac Magnetic Resonance Imaging of Epicardial and Intramyocardial Adiposity as an Early Sign of Myocardial Disease. Journal article Antonopoulos AS. and Antoniades C., (2018), Circ Cardiovasc Imaging, 11 Mechanisms of testosterone deficiency-related endothelial dysfunction: Invited commentary for the Hellenic Journal of Cardiology on: Tsikas et al. "Associations between asymmetric dimethylarginine, nitrite-dependent renal carbonic anhydrase activity and plasma testosterone levels in hypogonadal men". Journal article Antonopoulos AS. and Antoniades C., (2018), Hellenic J Cardiol, 59, 207 - 208 More publications © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement Site Map Accessibility Cookies Contact us Log in About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group Chapman Group: Genome stability and DNA repair mechanisms in cancer and genome diversification Patel Group People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Affaf Aliouat Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard Jordan Becker John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand Matt Brechin Serena Briant Linford Briant Anne Bridgeman Paul Brodersen James Brown Jill Brown Lynn Brown Connor Broyles Marella de Bruijn Alastair Buchan Veronica Buckle Paul Buckley Daniel Bulte Martijn van de Bunt Mario Buono Holger Burchert Emma Burke-Smith Oliver Burns Matthew Burrage Shijie Cai David Cain Sarah Califano Ivan Candido-Ferreira Fang Cao Maria Carena Maria Carena Ricardo Carnicer Davide Carone Joana Carrelha Brigid Carter Barbara Casadei Carla Cascone Kuan Cha Hedia Chagraoui Jem Chalk Keith Channon Ross Chapman Lise Chauveau Jane Cheeseman Yi-Ling Chen Jili Chen Qian Cheng Amy Chiu Robin Choudhury Constantinos Christodoulides Zoe Christodoulou Sandy Chu Surawee Chuaiphichai Aldo Ciau-Uitz Thomas Clague Sally-Ann Clark Kevin Clark Lynn Clee Liz Cloke Christopher Cole Ruth Coleman Huw Colin-York Michela Colombo Ismael da Conceicao Catriona Conway Daniel Cooke Kerrie Cope Anna Corby Thomas Cornfield Eduardo Calpena Corpas Yvonne Couch Mark Crabtree Fay Croft Heidi Crook Eloise Cross Nicholas Crump Andres Hueso Cuervo Nicola Curry Melinda Czéh Liangti Dai Andrea van Dam Rinita Dam Matt Daniels Lorna Daniels Carol Davey James Davies Graham Davies Simon Davis James Dean Rebecca Dean Atanasiu Stefan Demian Niall Dempster Louise Dennis Timothy Dent Geoffrey Denwood Michael Desborough Matthew Dickinson Marina Diotallevi Tomasz Dobrzycki Cameron Dockerill Michael Dodd Kathleen Dolan Hamid Dolatshad Robert Friedrich Donat Tao Dong Greig Dougall Patricia Douglas Gillian Douglas Damien Downes Hal Drakesmith Roy Drissen Edward Drydale Yue Du Claire Duff Sam Dunkley Pamela Dyson James Early James Eaton Carol Eaton Laurienne Edgar Christian Eggeling Mehroz Ehsan Jane Ellis Hanif Esmail Lise Estcourt Rachel Etherington Mark Evans Tracey Evans Martyn Ezra Anne Farmer Martin Farrall Oliver Featherstone Martin Fellermeyer Candida Fenton David Ferguson João Ferreira Fernandes Vanessa Ferreira Lucy Field Alison Fletcher Gary Ford


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262 www.rdm.ox.ac.uk/people/cameron-dockerill
263 www.rdm.ox.ac.uk/people/michael-dodd
264 www.rdm.ox.ac.uk/people/kathleen-dolan
265 www.rdm.ox.ac.uk/people/hamid-dolatshad
266 www.rdm.ox.ac.uk/people/robert-friedrich-donat
267 www.rdm.ox.ac.uk/people/tao-dong
268 www.rdm.ox.ac.uk/people/greig-dougall
269 www.rdm.ox.ac.uk/people/patricia-douglas
270 www.rdm.ox.ac.uk/people/gillian-douglas
271 www.rdm.ox.ac.uk/people/damien-downes
272 www.rdm.ox.ac.uk/people/alexander-drakesmith
273 www.rdm.ox.ac.uk/people/roy-drissen
274 www.rdm.ox.ac.uk/people/edward-drydale
275 www.rdm.ox.ac.uk/people/yue-du
276 www.rdm.ox.ac.uk/people/claire-duff
277 www.rdm.ox.ac.uk/people/samuel-dunkley
278 www.rdm.ox.ac.uk/people/pamela-dyson
279 www.rdm.ox.ac.uk/people/james-early
280 www.rdm.ox.ac.uk/people/james-eaton
281 www.rdm.ox.ac.uk/people/carol-eaton
282 www.rdm.ox.ac.uk/people/laurienne-gardner
283 www.rdm.ox.ac.uk/people/christian-eggeling
284 www.rdm.ox.ac.uk/people/mehroz-ehsan
285 www.rdm.ox.ac.uk/people/jane-ellis
286 www.rdm.ox.ac.uk/people/hanif-esmail
287 www.rdm.ox.ac.uk/people/lise-estcourt
288 www.rdm.ox.ac.uk/people/rachel-etherington
289 www.rdm.ox.ac.uk/people/mark-evans
290 www.rdm.ox.ac.uk/people/tracey-evans
291 www.rdm.ox.ac.uk/people/martyn-ezra
292 www.rdm.ox.ac.uk/people/anne-farmer
293 www.rdm.ox.ac.uk/people/martin-farrall
294 www.rdm.ox.ac.uk/people/oliver-featherstone
295 www.rdm.ox.ac.uk/people/martin-fellermeyer
296 www.rdm.ox.ac.uk/people/candida-fenton
297 www.rdm.ox.ac.uk/people/david-ferguson
298 www.rdm.ox.ac.uk/people/joao-ferreira-fernandes
299 www.rdm.ox.ac.uk/people/vanessa-ferreira
300 www.rdm.ox.ac.uk/people/lucy-field
301 www.rdm.ox.ac.uk/people/alison-fletcher
302 www.rdm.ox.ac.uk/people/gary-ford



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