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Title: Alastair Buchan — Radcliffe Department of Medicine
Description: Alastair Buchan - Professor of Stroke Medicine
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Texto: Alastair Buchan — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Skip to main content Site Map Accessibility Cookies Contact us Log in Menu Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Alastair Buchan Contact information Email alastair.buchan@medsci.ox.ac.uk PA Pramodi Majithia pramodi.majithia@medsci.ox.ac.uk Research groups Buchan Group: Laboratory of Cerebral Ischemia Buchan Group: Responsible Research and Innovation Colleges Corpus Christi College Alastair Buchan Professor of Stroke Medicine Pro-Vice-Chancellor (Head of Brexit Strategy) Acute stroke and Neuroprotection Prof Alastair Buchan heads the Laboratory of Cerebral Ischaemia whose aim is to identify novel neuroprotective strategies that may be used for the treatment or prevention of an acute stroke. We conduct preclinical studies on putative neuroprotectants in models of stroke, while running human studies to identify potential targets for treatment strategies and markers for monitoring patients. We take a multimodal approach that involves aspects of cell and molecular biology, physiology, pharmacology, in vivo imaging, surgery and clinical medicine. Our interests currently lie in many exciting avenues of stroke research. We are identifying and targeting novel neuroprotective pathways following brain ischaemia such as the oxygen sensing mechanism, hypoxia inducible factor (HIF). We are also using proteomic and metabolomic techniques to identify new biomarkers for stroke. Other avenues of research include investigating neurovascular coupling following stroke, exploring pericyte control of capillary blood flow as well as attempting to improve the efficacy of the only approved treatment for acute stroke, recombinant tissue plasminogen activator (rtPA). Recent publications A survey to explore new markers of achievement to assess and monitor gender equity in an NIHR Biomedical Research Centre: A two-factor model Journal article Henderson LR. et al, (2020) Investigation of the novel mTOR inhibitor AZD2014 in neuronal ischemia. Journal article Hadley G. et al, (2019), Neurosci Lett, 706, 223 - 230 Structural Transformation to Attain Responsible BIOSciences (STARBIOS2): Protocol for a Horizon 2020 Funded European Multicenter Project to Promote Responsible Research and Innovation. Journal article Colizzi V. et al, (2019), JMIR Res Protoc, 8 The effect of rapamycin treatment on cerebral ischemia: A systematic review and meta-analysis of animal model studies. Journal article Beard DJ. et al, (2019), Int J Stroke, 14, 137 - 145 New indicators and indexes for benchmarking university-industry-government innovation in medical and life science clusters: results from the European FP7 Regions of Knowledge HealthTIES project. Journal article Edmunds LD. et al, (2019), Health Res Policy Syst, 17 More publications © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Carole Bataille Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Nicolas Bery Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand Matt Brechin Serena Briant Linford Briant Anne Bridgeman Paul Brodersen James Brown Jill Brown Connor Broyles Marella de Bruijn Alastair Buchan Veronica Buckle Paul Buckley Daniel Bulte Martijn van de Bunt Mario Buono Holger Burchert Emma Burke-Smith Oliver Burns Matthew Burrage Shijie Cai David Cain Sarah Califano Ivan Candido-Ferreira Fang Cao Maria Carena Maria Carena Ricardo Carnicer Davide Carone Joana Carrelha Brigid Carter Barbara Casadei Carla Cascone Vincenzo Cerundolo Kuan Cha Hedia Chagraoui Jem Chalk Keith Channon Lise Chauveau Jane Cheeseman Yi-Ling Chen Jili Chen Qian Cheng Amy Chiu Robin Choudhury Constantinos Christodoulides Zoe Christodoulou Sandy Chu Surawee Chuaiphichai Aldo Ciau-Uitz Thomas Clague Sally-Ann Clark Kevin Clark Lynn Clee Liz Cloke Christopher Cole Ruth Coleman Huw Colin-York Michela Colombo Ismael da Conceicao Catriona Conway Daniel Cooke Kerrie Cope Anna Corby Thomas Cornfield Eduardo Calpena Corpas Yvonne Couch Mark Crabtree Fay Croft Heidi Crook Eloise Cross Nicholas Crump Andres Hueso Cuervo Melinda Czéh Liangti Dai Andrea van Dam Rinita Dam Matt Daniels Lorna Daniels Carol Davey James Davies Graham Davies Simon Davis James Dean Rebecca Dean Atanasiu Stefan Demian Niall Dempster Louise Dennis Timothy Dent Geoffrey Denwood Michael Desborough Veronica Alcolea Devesa Matthew Dickinson Marina Diotallevi Tomasz Dobrzycki Cameron Dockerill Michael Dodd Kathleen Dolan Hamid Dolatshad Robert Friedrich Donat Tao Dong Patricia Douglas Gillian Douglas Damien Downes Hal Drakesmith Roy Drissen Edward Drydale Yue Du Claire Duff Sam Dunkley Pamela Dyson James Early James Eaton Carol Eaton Laurienne Edgar Christian Eggeling Mehroz Ehsan Jane Ellis Hanif Esmail Lise Estcourt Rachel Etherington Mark Evans Tracey Evans Martyn Ezra Anne Farmer Martin Farrall Martin Fellermeyer Candida Fenton David Ferguson João Ferreira Fernandes Vanessa Ferreira Lucy Field Alison Fletcher Gary Ford Nicholas Fordham Helena Francis John Frankland Rachel Franklin Joe Frost Xiaopeng Fu


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267 www.rdm.ox.ac.uk/people/alexander-drakesmith
268 www.rdm.ox.ac.uk/people/roy-drissen
269 www.rdm.ox.ac.uk/people/edward-drydale
270 www.rdm.ox.ac.uk/people/yue-du
271 www.rdm.ox.ac.uk/people/claire-duff
272 www.rdm.ox.ac.uk/people/samuel-dunkley
273 www.rdm.ox.ac.uk/people/pamela-dyson
274 www.rdm.ox.ac.uk/people/james-early
275 www.rdm.ox.ac.uk/people/james-eaton
276 www.rdm.ox.ac.uk/people/carol-eaton
277 www.rdm.ox.ac.uk/people/laurienne-gardner
278 www.rdm.ox.ac.uk/people/christian-eggeling
279 www.rdm.ox.ac.uk/people/mehroz-ehsan
280 www.rdm.ox.ac.uk/people/jane-ellis
281 www.rdm.ox.ac.uk/people/hanif-esmail
282 www.rdm.ox.ac.uk/people/lise-estcourt
283 www.rdm.ox.ac.uk/people/rachel-etherington
284 www.rdm.ox.ac.uk/people/mark-evans
285 www.rdm.ox.ac.uk/people/tracey-evans
286 www.rdm.ox.ac.uk/people/martyn-ezra
287 www.rdm.ox.ac.uk/people/anne-farmer
288 www.rdm.ox.ac.uk/people/martin-farrall
289 www.rdm.ox.ac.uk/people/martin-fellermeyer
290 www.rdm.ox.ac.uk/people/candida-fenton
291 www.rdm.ox.ac.uk/people/david-ferguson
292 www.rdm.ox.ac.uk/people/joao-ferreira-fernandes
293 www.rdm.ox.ac.uk/people/vanessa-ferreira
294 www.rdm.ox.ac.uk/people/lucy-field
295 www.rdm.ox.ac.uk/people/alison-fletcher
296 www.rdm.ox.ac.uk/people/gary-ford
297 www.rdm.ox.ac.uk/people/nicholas-fordham
298 www.rdm.ox.ac.uk/people/helena-francis
299 www.rdm.ox.ac.uk/people/john-frankland
300 www.rdm.ox.ac.uk/people/rachel-franklin
301 www.rdm.ox.ac.uk/people/joe-frost
302 www.rdm.ox.ac.uk/people/xiaopeng-fu



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