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Title: Adrian Banning — Radcliffe Department of Medicine
Description: Adrian Banning - Professor of Interventional Cardiology
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Texto: Adrian Banning — Radcliffe Department of Medicine Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Site Map Accessibility Cookies Contact us Log in Home About us About us Our Divisions Our Clinical Facilities and MRC Units Working at RDM Athena SWAN News Seminars Locations and contact details Research People Study with us Work with us Current vacancies Novo Nordisk - Oxford Fellowships For Staff Contacts, travel and maps Personnel Finance, Grants and Funding Facilities, IT and Health and Safety Graduate Studies Career Development Athena SWAN Communications and public engagement Search People Adrian Banning Contact information Email adrian.banning@cardiov.ox.ac.uk Research groups Banning Group Adrian Banning Professor of Interventional Cardiology I perform translational research into mechanisms of injury in PCI  and understanding reperfusion in ST elevation myocardial injury.  Initially we demonstrated the importance of Troponin elevation after PCI as it reflects new myocardial injury detected by MR imaging.  .  We then investigated changes in blood flow in these newly injured areas and investigated the impact of opening chronic occlusions on myocardial function.  We completed a randomised controlled  trial of PCI vs CABG with evidence of new myocardial injury as the endpoint (Eurointervention January 2011).  Analysis of the role of different markers of injury in this study was published by J Am Coll Cardiol 2011 with an accompanying editorial.  This work helped change the biochemical definitions of revascularisation injury within subsequent trials of revascularisation strategy. We are currently investigating how to predict outcome in ST elevation myocardial infarction and how using these novel tools we might tailor therapy for those patients most at risk of adverse outcomes. Industry sponsored research I have been intimately involved with the initial clinical launch of drug eluting stents (DES) and championed the use of intravascular ultrasound (IVUS) within theUK. IVUS expertise was critical in being allowed to participate in landmark international interventional studies, eg Taxus and Endeavour.  These studies have complex entry requirements and require careful five year follow up including 2 follow-up angiograms and intravascular ultrasound studies.  Participation in these international clinical studies is subject to extremely intense scrutiny and external audit including review of individual angiograms, case records and outcomes.  I was the 2nd largest recruiter worldwide to Taxus 2 (Circulation 2003) At the time of recruitment, the TAXUS 6 study was the most complex pattern of disease then studied. I was the joint 3rd largest recruiter worldwide and a co author on the subsequent papers. The Syntax trial was a landmark randomized study comparing drug eluting stents with coronary surgery in patients with complex coronary disease.  I was the UK Principal Investigator (PI) for intervention and our centre became the 4th most successful recruitment centre in the world.  I was the first author on the second publication (J Am Coll Cardiol 2010) focussing on the diabetic subset. The HORIZONS trial was a randomised trial of patients undergoing primary PCI.  I was UK PI for this study and wrote the MREC application.E SELECT was a registry sponsored by Cordis. I was UK PI and international steering group member. (J Am Coll Cardiol 2012). More recently I randomised the first patient in the world into Excel, a trial of stents vs surgery for left main coronary disease (Abbott). Under my leadership Oxford recruiter the 2nd largest cohort of patients to this trial and I was one of the authors of the New England Journal of Medicine paper (2017) Service development research In 1999 we began day case treatment programmes for elective Percutaneous Coronary intervention (PCI).   Subsequently I started day transfer for urgent cases with acute coronary syndromes.  Both of these methods of service delivery were ground breaking and described in a peer review journal (Heart 2004).  Transfer required a unique collaboration with St Johns Ambulance to arrange the return service.  I obtained funding for this service from industry initially, until the NHS were prepared to cover the expense. In August 2007, launching region-wide Primary PCI required cooperation with Ambulance trusts, colleagues from surrounding hospitals and multidisciplinary teams.  This service has been successful in reducing hospital stay and probably improving outcomes.  Currently >280 AMI patients/annum are being treated and the programme will treat up to 550 cases by 2012  We were the first service in the UK to initiate paramedic delivery of clopidogrel in the community prior to hospital transfer  We were a reference site for the national NIAP project and our results were presented at the national launch of the report. I was part of the British Cardiovascular Society (BCS)/Royal College of Physicians (RCP) working group with Prof Bowling on ageism in health care (Heart 2000). I was co author of  guidelines for care for patients with valvular heart disease (BCS and RCP) and I am leading a number of projects into the management of patient with aortic stenosis and management with TAVI- percutaneous aortic valves.   Scopus h index 43- (accessed August 2017) Key publications Not So Fast: Complete Revascularization of the ST-Segment-Elevation Myocardial Infarction Patient Is Not Yet Proven. Journal article Bhindi R. and Banning AP., (2017), Circulation, 135, 1574 - 1576 Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial. Journal article Mäkikallio T. et al, (2016), Lancet, 388, 2743 - 2752 Myocardial infarction after percutaneous coronary intervention: a meta-analysis of troponin elevation applying the new universal definition. Journal article Testa L. et al, (2009), QJM, 102, 369 - 378 Residual ischemia after revascularization in multivessel coronary artery disease: insights from measurement of absolute myocardial blood flow using magnetic resonance imaging compared with angiographic assessment. Journal article Arnold JR. et al, (2013), Circ Cardiovasc Interv, 6, 237 - 245 Troponin elevation after percutaneous coronary intervention directly represents the extent of irreversible myocardial injury: insights from cardiovascular magnetic resonance imaging. Journal article Selvanayagam JB. et al, (2005), Circulation, 111, 1027 - 1032 Recent publications Mapping interventional cardiology in Europe: the European Association of Percutaneous Cardiovascular Interventions (EAPCI) Atlas Project. Journal article Barbato E. et al, (2020), Eur Heart J The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade. Journal article Kalla M. et al, (2020), Eur Heart J, 41, 2168 - 2179 Transcatheter aortic valve implantation via surgical subclavian versus direct aortic access: A United Kingdom analysis. Journal article Myat A. et al, (2020), Int J Cardiol, 308, 67 - 72 Angiography-derived index of microcirculatory resistance as a novel, pressure-wire-free tool to assess coronary microcirculation in ST elevation myocardial infarction. Journal article De Maria GL. et al, (2020), Int J Cardiovasc Imaging Reflectance spectral analysis for novel characterization and clinical assessment of aspirated coronary thrombi in patients with ST elevation myocardial infarction. Journal article De Maria GL. et al, (2020), Physiol Meas, 41 More publications © 2020 Radcliffe Department of Medicine Freedom of Information Privacy Policy Copyright Statement Accessibility Statement Site Map Accessibility Cookies Contact us Log in About us Our Divisions Investigative Medicine Division Nuffield Division of Clinical Laboratory Sciences Oxford Centre for Diabetes, Endocrinology and Metabolism Division of Cardiovascular Medicine MRC Weatherall Institute of Molecular Medicine MRC Weatherall Institute of Molecular Medicine Our Clinical Facilities and MRC Units Acute Vascular Imaging Centre Cardiovascular Clinical Research Facility Oxford Centre for Clinical Magnetic Resonance Research Working at RDM Equal career opportunities and flexible working Career development and training Athena SWAN News Seminars Locations and contact details Research Cardiovascular Science Haematology and Pathology Diabetes, Metabolism and Endocrinology Cancer Biology Immunology and Infection Stem Cells and Developmental Biology Geratology Experimental Therapeutics Ashrafian Group: Experimental Therapeutics and Clinical Pharmacology Mahmod group Tyler Group Lunter Group: Functional Genomics & Machine Learning Lunter Group Chapman Group: Genome stability and DNA repair mechanisms in cancer and genome diversification Patel Group People Moustafa Abdalla Ines Abdesselam Adib Abdullah Amanda Adler Satish Adwani Devika Agarwal Olorunsola Agbaje Doaa Ahmed Jila Ajeian Nadia Akawi Naveed Akbar Nasren Akhtar Ioannis Akoumianakis Merve Aksoz Marta Perez Alcantara Yara Alenazi Affaf Aliouat Jack Allen Maryam Alsharqi Sneha Anand Amanda Anderson Agata Antepowicz Charalambos Antoniades Alex Antonopoulos Mahesh Appari Andrew Apps Janhavi Apte Rina Ariga Andrew Armitage Alyssa Armsby Linda Arnold Ritu Arya James Ashford Neil Ashley Nicole Ashman Houman Ashrafian Kate Attfield Christian Babbs Mohsin Badat Ileana Badi Jade Bailey Subita Balaram Abhirup Banerjee Alison Banham Adrian Banning Liliana Barbieri Mike Barnkob Amy Barrett Matthew Baxter Asha Bayliss Robert Beagrie Daniel Beard Jordan Becker John Bell John Bell Elena Benedetto Amanda Bennett Felicity Bennett Timothy Betts Ryan Beveridge Shoumo Bhattacharya William Biggs Malenka Bissell Edward Blair Henry Blest Nicholas Blockley Henry Boardman Andrea Borghetto Alessandra Borlotti Jacqueline Boultwood Yavor Bozhilov Adam Braithwaite Robert Brand Matt Brechin Serena Briant Linford Briant Anne Bridgeman Paul Brodersen James Brown Jill Brown Lynn Brown Connor Broyles Marella de Bruijn Alastair Buchan Veronica Buckle Paul Buckley Daniel Bulte Martijn van de Bunt Mario Buono Holger Burchert Emma Burke-Smith Oliver Burns Matthew Burrage Shijie Cai David Cain Sarah Califano Ivan Candido-Ferreira Fang Cao Maria Carena Maria Carena Ricardo Carnicer Davide Carone Joana Carrelha Brigid Carter Barbara Casadei Carla Cascone Kuan Cha Hedia Chagraoui Jem Chalk Keith Channon Ross Chapman Lise Chauveau Jane Cheeseman Yi-Ling Chen Jili Chen Qian Cheng Amy Chiu Robin Choudhury Constantinos Christodoulides Zoe Christodoulou Sandy Chu Surawee Chuaiphichai Aldo Ciau-Uitz Thomas Clague Sally-Ann Clark Kevin Clark Lynn Clee Liz Cloke Christopher Cole Ruth Coleman Huw Colin-York Michela Colombo Ismael da Conceicao Catriona Conway Daniel Cooke Kerrie Cope Anna Corby Thomas Cornfield Eduardo Calpena Corpas Yvonne Couch Mark Crabtree Fay Croft Heidi Crook Eloise Cross Nicholas Crump Andres Hueso Cuervo Nicola Curry Melinda Czéh Liangti Dai Andrea van Dam Rinita Dam


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233 www.rdm.ox.ac.uk/people/daniel-cooke
234 www.rdm.ox.ac.uk/people/kerrie-cope
235 www.rdm.ox.ac.uk/people/anna-corby
236 www.rdm.ox.ac.uk/people/thomas-cornfield
237 www.rdm.ox.ac.uk/people/eduardo-calpena-corpas
238 www.rdm.ox.ac.uk/people/yvonne-couch
239 www.rdm.ox.ac.uk/people/mark-crabtree
240 www.rdm.ox.ac.uk/people/fay-croft
241 www.rdm.ox.ac.uk/people/heidi-crook
242 www.rdm.ox.ac.uk/people/eloise-cross
243 www.rdm.ox.ac.uk/people/nicholas-crump
244 www.rdm.ox.ac.uk/people/andres-hueso-cuervo
245 www.rdm.ox.ac.uk/people/nicola-curry
246 www.rdm.ox.ac.uk/people/melinda-czeh
247 www.rdm.ox.ac.uk/people/liangti-dai
248 www.rdm.ox.ac.uk/people/andrea-vandam
249 www.rdm.ox.ac.uk/people/rinita-dam



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