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Title: Rebeccah Slater — Department of Paediatrics
Description: PhD MSc BSc ARSM Rebeccah Slater - Professor of Paediatric Neuroscience
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Texto: Rebeccah Slater — Department of Paediatrics Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Find out more Site Map Accessibility Cookies Contact us Log in Home About us News Events Research Recent publications Study with us Work with Us Our team Search Our team Rebeccah Slater Contact information Email rebeccah.slater@paediatrics.ox.ac.uk Telephone 01865 234 229 Biography   Rebeccah Slater is Professor of Paediatric Neuroscience and a Senior Wellcome Trust Research Fellow. She is also a Professorial Fellow at St John's College. Rebeccah studied Physics (BSc) at Imperial College and Neuroscience (MSc) at UCL, and in 2007 was awarded her PhD at UCL under the supervision of Prof Maria Fitzgerald. Since 2013 she has led the Paediatric Neuroimaging Research Group, which focuses on understanding the mechanisms that underlie the development of pain perception in the human infant. She uses a range of non-invasive brain imaging tools, including EEG and fMRI, to explore the development of pain perception in the human nervous system. She has published many articles about infant pain and has been passionately involved in science communication and the public engagement of science. She has taken part in numerous discussions on TV and radio, including BBC Radio 4 and the BBC World Service. Rebeccah holds an honorary research position in the Neonatal Care Services at the John Radcliffe Children’s Hospital and is a PI at the Wellcome Centre for Integrative Neuroimaging (WIN).  Find out more about the Poppi Trial   - a Randomised Controlled Trial investigating the analgesic efficacy of morphine in premature infants. Rebeccah Slater PhD MSc BSc ARSM Professor of Paediatric Neuroscience Senior Wellcome Trust Research Fellow Understanding the mechanisms that drive the development of pain perception in the human infant My Research Pain in infancy has negative long-term consequences and its prevention is a clinical priority, but adequate treatment requires mechanistic understanding of the structural and functional development of human nociceptive circuitry. My research group aims to understand the mechanisms that drive and modulate pain perception in early human development. Recent scientific advances provide insights into how noxious information is transmitted to the infant brain, providing a platform to ask how intrinsic brain network connectivity and the environment affect noxious-evoked brain activity, behaviour and ultimately pain perception in the developing infant nervous system. We are investigating whether inherent differences in how the brain behaves at rest influence variability in noxious-evoked activity, and will determine how this relationship is altered by environmental factors and pathology. We want to understand how the development of structural and functional network connectivity alters noxious-evoked brain activity, and influences the dynamic relationship between brain activity and behaviour. The overarching goal is that this developmental understanding will  translate into the improved treatment of infant pain in premature and term-born infants.   Key publications Nociceptive brain activity as a measure of analgesic efficacy in infants. Journal article Hartley C. et al, (2017), Sci Transl Med, 9 Changing Balance of Spinal Cord Excitability and Nociceptive Brain Activity in Early Human Development. Journal article Hartley C. et al, (2016), Curr Biol, 26, 1998 - 2002 fMRI reveals neural activity overlap between adult and infant pain. Journal article Goksan S. et al, (2015), Elife, 4 Oral sucrose as an analgesic drug for procedural pain in newborn infants: a randomised controlled trial. Journal article Slater R. et al, (2010), Lancet, 376, 1225 - 1232 Analgesic efficacy and safety of morphine in the Procedural Pain in Premature Infants (Poppi) study: randomised placebo-controlled trial. Journal article Hartley C. et al, (2018), Lancet, 392, 2595 - 2605 Recent publications Preemptive Morphine during Therapeutic Hypothermia after Neonatal Encephalopathy: A Secondary Analysis Journal article Liow N. et al, (2020), Therapeutic Hypothermia and Temperature Management, 10, 45 - 52 Author Correction: A tool for functional brain imaging with lifespan compliance. Journal article Hill RM. et al, (2019), Nature communications, 10 Multimodal pain assessment improves discrimination between noxious and non‐noxious stimuli in infants Journal article Vaart M. et al, (2019), Paediatric and Neonatal Pain, 1, 21 - 30 A tool for functional brain imaging with lifetime compliance Journal article Hill R. et al, (2019), Nature Communications Nociception and the neonatal brain. Journal article Gursul D. et al, (2019), Semin Fetal Neonatal Med More publications Websites Google Scholar Scopus Researchgate © 2020 University of Oxford, Department of Paediatrics, Level 2, Children's Hospital, John Radcliffe, Headington, Oxford, OX3 9DU Freedom of Information Privacy Policy Copyright Statement Accessibility Statement Site Map Accessibility Cookies Contact us Log in About us Contact Us Funding our research A history of paediatrics at Oxford Learn more about our research Alumni News EUCLIDS Study investigates responses to Meningitis B vaccination Noxious Stimulation in Children Receiving General Anaesthesia Evokes an Increase in Delta Frequency Brain Activity Oxford Vaccine Group in Oxford MedSci News Oxford Vaccine Group launches Paratyphoid study Meningitis B Vaccine recommended for introduction into UK schedule OVG Typhoid study volunteers interviewed by the BBC Hitting the top spot for student satisfaction Innovation in good health at Oxford University Hospital Medical School Prize winners announced Athena SWAN awards for nine University departments Professor Irene Roberts appointed NIHR Theme Lead Dr. Eleni Louka awarded NIHR Fellowship OSOP presents: Careers in Paediatrics OSOP Presents: Working in Child Protection Pop-up Science pulls in the public Centre for Clinical Vaccinology and Tropical Medicine 10th Anniversary HIV Research Group receive major Wellcome Trust award £18.5m to train future bioscience leaders Oxford ranked number 1 for Clinical, Pre-Clinical and Health-related subjects Calling the shots - OMSG Article New vaccine generates strong immune response against hepatitis C From the Minds of Babes: New Frontiers in Paediatric Pain Research suggests ability of HIV to cause AIDS is slowing Oxford Medical Sciences excels in REF 2014 exercise Thinking Postgraduate? Think Oxford Oxford Vaccine Group begins first trial of new Ebola vaccine NIHR Oxford Biomedical Research Centre Open Weeks 2015 OSOP Presents: Bridging the gap between primary and secondary care services for children Oxford secures £139m in HEFCE research funding Investigating Meningococcal Vaccines in Adults Babies feel pain ‘like adults’ Fundraising campaign reaches £2 billion - and counting Professor Louise Richardson nominated as next Vice-Chancellor Professor of Paediatrics successfully defends her PhD 80 years later than originally planned Participate in our new Ebola study Oxford Ebola vaccine study moves to next phase Towards the prevention of RSV: A major cause of infant death Very premature and underweight babies are at risk of growing up as neurotic adults Vaccines Against Salmonella Typhi: Call for Participants Vaccine for common childhood infection may finally be possible Vaccine Knowledge App Graduate courses now open for 2016/17 Ebola Medals for Research Team Prestigious NIHR grant awarded to Rebeccah Slater Care 24/7: Making the clinical handover safe Applications open for the D.Phil in Infection, Immunology, and Translational Medicine Volunteers sought for study into vaccine for serious childhood infection Understanding the genetic basis for immune responses to flu vaccines in children and adults Nepal Earthquake - Experiences from our colleagues Dr Manish Sadaranganis wins Communications Prize at the Academy of Medical Sciences Nepal research has lessons for global vaccination efforts New Vice-Chancellor pledges ‘innovative, creative’ future for Oxford Oxford Experimental Psychology - Experimental Psychology mourns the sudden death of Professor Glyn Humphreys Andrew Pollard has been awarded a Principal Fellowship by the Oxford Biomedical Research Centre Why Mark Zuckerberg was right to vaccinate his daughter What is meningitis B – and why don’t older children get the vaccine? Dr Matthew Snape on 'Pikin to Pikin Tok' Measles and the MMR Vaccine Children with cancer given hope of having a family in the future Would you like your child to be vaccinated against chickenpox? Future of Oxford Chair in Developmental Medicine secured with £3.3million gift Would you like to help develop new typhoid vaccines? Partnership announces publication of positive phase 1 data for Ebola vaccine regimen It’s World Immunisation Week! Herd Immunity: How does it work? We need more nurses! Graduate Scholarship in Paediatrics Soapbox Science Dr Matthew Snape wins prize for engaging the public Neonatologist Dominic Wilkinson has been made Professor Georg Hollander and Andrew Pollard join the Fellowship of the Academy of Medical Sciences Everything you need to know about chickenpox and why more countries don’t use the vaccine Babies' painkiller problem Study suggests routes to improved immunity in older people Children could point the way to new HIV treatments Going Viral An international consortium, which includes the Department's Oxford Vaccine Group Receives $36.9 Million Grant to Fight Typhoid World Pneumonia Day: Making vaccines work to prevent pneumonia When art and science meet World AIDS Day 2016 University of Oxford launches Public Engagement with Research Strategic Plan Marta Valente Pinto receives Public Engagement Award from the University Oxford Science Blog-Detecting Counterfeit Medicines Brain Diaries: infant pain BBC: Would you trial an Ebola vaccine? 'Two-part Ebola vaccine offers long-lasting protection'


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