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Texto: Welcome — Department of Oncology Cookies on this website We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings. Continue Site Map Accessibility Cookies Contact us Log in Intranet Home About Us Research Clinical Trials Study with Us Our team News Blog Events Search © Shutterstock Immunology In the Division of Cancer Medicine we are working to further understand the interplay between the immune system and cancer across both cancer development and treatment. Read more Tumour Microenvironment Understanding how the tumour microenvironment affects cancer cell behaviour and how it contributes to a cancer cell’s response to ionising radiation is essential in understanding how to prevent the establishment, growth and progression of cancers and how to exploit the tumour microenvironment for therapeutic gain. Read more © Shutterstock Metabolism Metabolism is at the interface of oncogenic signalling, it is essential for tumour growth and all the Hallmarks of Cancer. Additionally, the local microenvironment is modelled by metabolism, which has major influences on the immune response. Read more © Shutterstock DNA Damage and Repair Understanding DNA damage and repair mechanisms helps researchers to identify the aberrant processes that drive cancer development and growth. Read more Translational Research A key aim of the Department of Oncology is the optimal translation of fundamental research into patient benefit. Precision cancer medicine brings together the concepts of biological selection of therapy with anatomical and functional targeting of treatment to deliver the best possible outcomes for a patient with cancer. Read more Genome Integrity & Epigenetics Our basic research into genome stability explores how cells repair damaged DNA to prevent cancer. We are also interested in what happens once cancer develops, as it is becoming clear that many tumours are defective in repairing damaged DNA. Our work aims to exploit these repair defects to design novel therapies. Read more © Shutterstock Clinical Trials A key aim of the Department of Oncology is the optimal translation of fundamental research into patient benefit and for Oxford to become the leading centre for translational early-phase oncology trials in the UK. Read more From our Head of Department Professor Mark Middleton Welcome to the The Department of Oncology. The Department of Oncology's mission is to improve cancer care through research and teaching. There is strong emphasis on translation, with established infrastructure to develop scientific insights toward clinical appreciation. The Department houses over 400 staff and postgraduate students - both clinical and non-clinical - and is one of the largest departments in the U niversity of Oxford's Medical Sciences Division. It is also home to the Institute for Radiation Oncology. One of the key aims for the Department is to bring together basic scientific and clinical research groups from across Oxford - based in the Old Road Campus Research  Building, the Radiobiology Research Institute, the Weatherall Institute for Molecular Medicine and the NHS Cancer and Haematology Centre - to apply knowledge of cancer and to develop research so that we may better understand how we can combat cancer in the most effective way possible. MRC Oxford Institute for Radiation Oncology The mission of the MRC Oxford Institute for Radiation Oncology is to explore aspects of radiation biology research that could yield new advances in the treatment of cancer. Find out more Division of Cancer Medicine The aims of the Division of Cancer Medicine are to understand cancer and the biological processes that govern how it starts, how it behaves and how the body responds to it. Find out more Our News Reprogramming tumour cells using an antimalarial drug 17 February 2021 Results from the ATOM clinical trial at the University of Oxford have shown that the anti-malarial drug Atovaquone can reduce very low oxygen tumour environments. This has the potential to make cancers behave less aggressively and to improve the impact of everyday cancer treatments. Global Young Scientists Summit 2021 11 February 2021 Hidden lung damage from COVID-19 revealed in new study 2 December 2020 Early findings from a study into longer-term damage amongst patients recovering from COVID-19 suggest that the use of cutting-edge scanning techniques may detect previously unseen lung damage. Professor Sibson secures further MRC DPFS funding 20 October 2020 Prof. Sibson together with her co-applicants Prof. Anthony, Dr Campbell and Prof. Middleton have now been awarded a second MRC DPFS grant, for £3.3 million, to acquire further preclinical data to support the case for clinical translation, to develop the mutTNF production for human use and to undertake pre-clinical toxicology. More news Accessibility Statement Copyright Statement Data Privacy Notice Freedom of Information Sitemap Site Map Accessibility Cookies Contact us Log in Intranet Welcome About Us About Us Division of Cancer Medicine MRC Oxford Institute for Radiation Oncology 60 seconds with... Working with us Family Friendly Training & Development Current Vacancies Athena SWAN Oncology Postdoctoral Network (OPN) Departmental Mentoring Scheme Seminars & Events Contact Us Research Tumour Microenvironment Immunology Metabolism Genome Integrity & Epigenetics Translational Research DNA Damage & Repair Scientific Research Facilities Early Phase Clinical Trials Unit Mechanical Workshop Pre-Clinical Imaging Microscopy Oncology Clinical Trials Office (OCTO) PET Radiochemistry and Radiopharmacy (PROx) Radiation Biophysics Translational Histopathology Flow Cytometry Proteomics Live Tissue Facility Research Group Adjuvant Colorectal Cancer Anticancer Viruses and Cancer Vaccines Cancer and Immunogenetics Cancer Cell Cycle Cancer Therapeutics and mRNA Dysregulation Cancer Therapeutics, DNA Damage & Repair Cell Cycle and Ubiquitin Signalling Cell Signalling Chromosome Integrity Computational Biology and Integrative Genomics DNA Damage & Disease DNA Damage Response DNA Repair in Cancer Treatment Early Phase Clinical Trials & Melanoma Therapy Experimental Neuroimaging Genomics of Inflammation and Cancer Immunology Genome Stability and Tumourigenesis Novel Clinical Imaging Research Nucleic Acids Oncological Image Analysis Oxford Molecular Diagnostics Experimental Radiotherapeutics Radiopharmaceuticals and Molecular Imaging Tumour Hypoxia Tumour Radiosensitivity DNA Damage and Repair Clinical Trials Site Early Phase Clinical Trials Unit (EPCTU) About Us What are Early Phase Clinical Trials? The Phase II Clinical Trial What happens after referral? Working at EPCTU How to find the Early Phase Clinical Trials Unit FAQs Further Information Oncology Clinical Trials Office About Us Work With Us Information for Patients, their Families and Carers Current Trials Trials in Set Up Completed Trials Study with


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